演題抄録

International Symposium

開催概要
開催回
第51回・2013年・京都
 

EBV DNA risk stratification and novel treatment strategies in nasopharynx cancer

演題番号 : IS3-3

[筆頭演者]
Tak Cheung Anthony Chan:1 

1:Department of Clinical Oncology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong

 

Despite excellent local control after intensity modulated radiotherapy with or without concurrent chemotherapy, the rate of distant failure remains high for stages IIB and above nasopharynx cancer (NPC). Post-treatment residual EBV DNA levels may provide a window of opportunity to risk stratify patients for adjuvant chemotherapy and a multicenter study hosted by the Hong Kong NPC Study Group is near completion while an international study hosted by RTOG is about to initiate. Results from phase II anti-epidermal growth factor receptor and anti-angiogenesis studies in metastatic and locoregionally advanced diseases have been promising. These may form the basis for future phase III studies.

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