演題抄録

口演

開催概要
開催回
第58回・2020年・京都
 

優秀演題
2cm以下膵神経内分泌腫瘍切除における予後因子の検討

演題番号 : O29-3

[筆頭演者]
播本 憲史:1 
[共同演者]
石井 範洋:1、塚越 真梨子:1、五十嵐 隆通:1、渡辺 亮:1、久保 憲生:1、新木 健一郎:1、調 憲:1、細内 康男:2、鈴木 秀樹:5、荒川 和久:4、平井 健太郎:3、深澤 正晴:6、伊古田 勇人:7

1:群馬大学・肝胆膵外科、2:前橋病院・外科、3:高崎総合医療センター・消化器外科、4:前橋赤十字病院・外科、5:伊勢崎市民病院・外科、6:群馬中央病院・外科、7:群馬大学・病態病理学

 

Background In this study, we investigated the malignant potential in patients with small well-differentiated pancreatic neuroendocrine tumor (PanNET) according to the WHO2017 classification.
Methods We retrospectively collected data for patients with PanNET 2cm in size who underwent pancreatic resection with curative intent between January 2008 and January 2018 at 6 institutions. Total 51 patients were analyzed in this study. We compared the clinicopathological factors and recurrence between tumor ≦15mm and >15mm.Results Patients with ≦15mm were significantly associated with larger tumor size, higher Ki-67 index, higher mitotic count, higher ki-67 index, high incidence of lymph node metastasis and neutrophil lymphocyte ratio. Uni-variate analysis identified >15mm in size, NET G2 or G3, lymph node metastasis, high NLR, ly(+),v(+) and ne(+) as independent risk factors for recurrence. There are no significant factor in multi-variate analysis for recurrence.Conclusions Routine pancreatetomy and lymph node dissection was needed in patients with PanNET>15mm ≦2cm in size. Further study will be needed in PanNET≦15mm.

キーワード

臓器別:膵臓

手法別:手術療法

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