演題番号 : P94-4
Uterine cervical cancer sometimes remains in the cervix even after curative radiotherapy (RT) or concurrent chemoradiotherapy (CCRT). There are some clinical data about patients treated by salvage hysterectomy for residual tumor. On the other hand, there is limited data about patients who undergo observation. The objective of this study is to investigate clinical courses in patients with residual tumor who have undergone observation even though salvage hysterectomy could be an indication.
From 61 patients with FIGO Stage IB-II cervical cancer who underwent curative RT/CCRT at our institution between 2007 and 2014, we selected patients who had been diagnosed with or were suspected to have residual tumor by cytology or biopsy within 3 months of the completion of irradiation. Exclusion criteria was as follows: Over 75 years old and with tumor located outside of uterine cervix.
We enrolled 11 patients, of whom the median age was 63 years old (range 23 - 74). The distribution of FIGO stage was as follows: IB1 3, IB2 2, IIA1 4, and IIB 2. Ten patients had squamous cell carcinoma, and one patient had adenocarcinoma. Six patients underwent RT and five underwent CCRT. All patients underwent observation and the disappearance of the residual disease was confirmed at a later date. The median time to disappearance was 99 days (range 58 - 206). There were no fatal outcomes.
Even if residual tumors are suspected based on cytology or biopsy within three months from the completion of RT/CCRT, tumor disappearance can be achieved while undergoing careful observation, and salvage hysterectomy can be avoided.