演題抄録

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開催概要
開催回
第56回・2018年・横浜
 

当院における膵神経内分泌腫瘍の検討

演題番号 : P110-3

[筆頭演者]
演者)小川 敦:1 
[共同演者]
持田 泰:1、山田 和之介:1、鈴木 雅貴:1、小澤 大悟:1、深井 康幸:1、尾嶋 仁:1

1:群馬県立がんセンター・消化器外科

 

BACKGROUND: Neuroendocrine tumor (NET) is an unusual tumor, but in recent years, its morbidity has been increasing. Most of NET occurs in the gastrointestinal tract, and about 6% is called pancreatic neuroendocrine tumor (PNET) and it is rarely encountered in clinical practice. We report on cases in which we underwent operation after diagnosis of pancreatic neuroendocrine tumor (PNET) at our hospital.

METHODS: We examined 8 cases diagnosed as PNET from October 2005 to October 2014 and underwent surgery at our hospital. It was studied clinical background factors and pathological diagnosis

RESULTS: The average age was 61 years, of which 5 were female. Five cases were found during medical chekup and examination of other diseases. Two cases were accidentally found in resected specimens for pancreatic cancer and IPMN main pancreatic duct type. Functional NET was only one case, and the production hormone was insulin, which resulted in diagnosis due to repeated hypoglycemic attacks. In all cases, distal metastasis and lymph node metastasis were not recognized and curative surgery could be performed. There were no cases in which adjuvant chemotherapy was performed after surgery. During the follow-up period, none of the patients who died of the original disease was admitted. In pathological findings, G1 was 2 cases, G2 was 6 cases, and G3 was not admitted.(Some are being added immunostaining)

DISCUSSION: We examined cases in which we could undergo curative surgery and diagnosed as PNET at our hospital. Except for one case of insulin-producing tumor, all cases were asymptomatic at the time of discovery. Although radical resection was possible in all cases, there were no G3 cases, which is known as poor prognosis. In other words, it means that G3 in PNET was not possible curative resection at the time of discovery. In PNET, surgery is the most effective treatment that can be curable in the current, so early detection before metastasis is indispensable.

キーワード

臓器別:NET(神経内分泌腫瘍)

手法別:手術療法

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