演題抄録

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開催概要
開催回
第56回・2018年・横浜
 

原発不明癌として当科を受診した59例の検討

演題番号 : P108-4

[筆頭演者]
演者)高橋 鴻志:1,2 
[共同演者]
鈴木 修平:1、福井 忠久:1、中村 翔:1、武田 弘幸:1、渡邉 要:1、鈴木 尚樹:1、吉岡 孝志:1

1:山形大学・臨床腫瘍学、2:山形県立新庄病院・内科

 

Purpose: CUP, carcinoma of unknown primary, accounts for 2% of all malignant tumors,and its prognosis is still poor. We evaluated the treatment and the outcome of CUP caseswe experienced in 2013-2018.Method: From October 2013 to April 2018, 59 patients were referred to YamagataUniversity Hospital Clinical Oncology department as CUP. After the additional examination,30 patients were diagnosed as CUP. We investigated them retrospectively, and consideredabout the medication and prognostic factor.Result: Male: Female = 50%: 50%, and the median age was 64. The median survival timewas 290 days and the median overall survival time of the patients who receivedchemotherapy (almost PAC+CBDCA) was 335 days (as a reference, 280 days with 47 CUPcases in 2008-2013). The median time to first line treatment failure was 136 days (secondline: 90 days, third line: 130 days). The objective response rate was 23%. Mild correlationwith the outcome was observed in the factor of family history, favorable subset andtreatment response in univariate and multivariate analysis.Conclusion: In this retrospective study, the outcome of the CUP patients we experiencedwas similar with the previous report and still severe. The improvement of the treatmentresults is strongly needed.

キーワード

臓器別:その他

手法別:疫学・予防

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