演題番号 : O49-3
In recent years, cancer chemotherapy is being conducted at outpatient clinics, wherein pharmacists are involved with patient guidance and the management of adverse events as experts in medication therapy. However, the relationship between pharmacist involvement and patient quality of life has not been clarified. Therefore, the purpose of this study was to clarify the influence of pharmacist involvement during the counseling of patients with cancer on patients' quality of life.
We conducted a survey to assess the quality of life of 39 patients with breast cancer who underwent their initial course of outpatient cancer chemotherapy at Gifu Municipal Hospital from 2013 to 2015. Patients completed the quality of life survey immediately before the 1st, 2nd, and 3rd courses of treatment. The survey was based on an instrument obtained from a paper entitled, "Quality of Life Questionnaire for Cancer Patients Treated with Anticancer Drugs." Data on the patients' side effects of chemotherapy were obtained from electronic medical records.
Twenty patients were assigned to the counseling group, which received pharmacist counseling. Nineteen patients were assigned to the observation group, which received no pharmacist counseling. Nausea, alopecia, and anorexia were the side effects that occurred in more than half of patients. Significant group differences in the change from before the 1st to 3rd course of treatment were found on total quality of life and the subscales of social relationships for nausea (p=0.049, p=0.006, respectively).
Results suggest that receiving pharmacists' guidance on adverse events and individually adjusted prescriptions tailored to address the occurrence of adverse events improved the treatment environment and enhanced the quality of life in the counseling group. These findings are beneficial in maintaining patients' quality of life during cancer treatment.