演題抄録

FACO Poster Session

開催概要
開催回
第56回・2018年・横浜
 

Radiofrequency ablation versus laparoscopic hepatectomy for hepatocellular carcinoma:a propensity score matching study

演題番号 : FP1-26

[筆頭演者]
Speaker)Yangxun Pan:1 
[共同演者]
Minjiang Yi:1、Jinbin Chen:1、Juncheng Wang:1、Yaojun Zhang:1、Li Xu:1、Minshan Chen:1、Zhongguo Zhou:1

1:Department of Hepatobiliary & Pancreatic Surgery, Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, China

 

Background: Both radiofrequency ablation (RFA) and laparoscopic hepatectomy (LH) are first choice asminimally invasive approach for hepatocellular carcinoma (HCC) at early stage. This study aimed to compare theefficacy of RFA and LH for treating HCC with a large cohort.Methods: From March 2014 to July 2016, 484 consecutive patients who underwent RFA (n=314) or LH (n=170)for HCC tumors ≦5.0 cm were included. Overall survival (OS) and recurrence-free survival (RFS) werecompared. Propensity score matching (PSM) was performed to correct potential confounding factors.Results: Collectively, the 1-, 2- and 3-year OS rates were significantly greater after LH than RFA, as were thecorresponding RFS rates, before and after PSM by 2:1. The RFA group had fewer major complications(p=0.004), shorter hospitalization times (p<0.001) and lower hospital charges (p<0.001) than the LH group. Inthe subgroup analysis, although there was no significant difference in OS (p=0.723) for tumors in central sections(SIV, SV, SVIII), the RFS was better in the LH group than the RFA group (p=0.004). The male sex, hepatitis Bvirus infection, tumor number and treatment type were significant prognostic factors for OS; the latter two werealso factors for RFS.Conclusions: Though, LH was superior than RFA in most condition of tumor smaller than 5 cm, the RFA couldbe an optimal approach achieved comparable OS and RFS in patients with HCC tumors less than 3 cm located incentral bisections, with fewer major complications, shorter hospital stays and lower hospital charges.

キーワード

臓器別:Liver

手法別:Surgical Techniques

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