演題抄録

一般演題 (示説)

開催概要
開催回
第54回・2016年・横浜
 

Mammography versus ultrasound for breast cancer screening in Asian women

演題番号 : P85-5

[筆頭演者]
Ding Lan Jun:1 
[共同演者]
Liang Xuan:1、Wang Yuan:1

1:Tianjin Medical University, China・School of Publish Health・Epidemiology and Health Statistics

 

Background: Mammography has been used for screening breast cancer for decades with high efficacy on reducing the mortality in most western countries, while ultrasonography has been disputed with a better screening efficacy in women with small and dense breast. However, the controversy of these 2 methods varied.
Objectives: To compare the screening efficacy of mammography and ultrasonography among Asian women.
Methods: PubMed (4 January 2016), Embase Biomedical Database (4 January 2016) and Cochrane Database of Systematic Reviews (4 January 2016) were searched by two independent authors. Available articles published between January 2000 and January 2016 with complete data and appreciated eligibility were included. We extracted studies with high risk of bias or controversy.
Results: We identified twenty-three relevant studies, six of eligible studies were included in this meta-analysis of comparison between mammography and ultrasonography among Asian women aged 25-87 years (42262 screened by mammography screening and 40135 by ultrasonography). The sensitivity, specificity, SROC Curve AUC, positive Likelihood ratio and negative Likelihood ratio were 0.79(CI, 0.69 to 0.86), 0.98(CI, 0.92 to 1.00), 0.88(CI, 0.85 to 0.90), 41.3(CI, 9.8 to 174.3) and 0.22(CI, 0.15 to 0.31) for mammography, 0.69(CI, 0.58 to 0.79), 0.99(CI, 0.94 to 1.00), 0.84(CI, 0.81 to 0.87), 55.0(CI, 9.9 to 304.1) and 0.31(CI, 0.21 to 0.45) for ultrasonography respectively.
Conclusions: There was no significant difference between the efficacy of mammography and ultrasonography when screening Asian women in average or high risk for breast cancer. These results suggest that ultrasonography can be worth considering in breast cancer screening among large population.

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臓器別:乳腺

手法別:臨床試験

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