演題抄録

一般演題 (示説)

開催概要
開催回
第54回・2016年・横浜
 

Multicentric colorectal cancer screening in a developing country

演題番号 : P85-1

[筆頭演者]
Zarate Alejandro J.:1 
[共同演者]
Lopez - Kostner Francisco:1、Kronberg Udo:1、Ponce Alejandra:1、Zamorano Diego:1、Peñaloza Paulina:1、Kawachi Hiroshi:2、Okada Takuya:2、Tsubaki Masahiro:2、Odagaki Tomoyuki:2、Ito Takashi:2、Eishi Yoshinobu:2、Estela Ricardo:3、Karelovic Stanko:4、Flores Sergio:5

1:Clínica Las Condes, Chile・Colorectal Unit、2:Tokyo Medical and Dental University (TMDU)、3:Hospital Clínico San Borja Arriarán (HCSBA)、4:Hospital Clínico de Magallanes、5:Hospital Eduardo Pereira

 

Purpose: Colorectal cancer screening programs (CRCSP) are performed in most developed countries. Due to resources restrictions CRCSP are very unlikely in developing countries. Aim: To analyze a multicentric prospective CRCSP in Chile.
Methods: In order to improve the efficiency, a special program design was performed and health´s professional from three Public Hospitals (Santiago, Valparaiso and Punta Arenas) were trained to improve people´s education (iFOBT adherence and adequate bowel preparation). On the other hand colonoscopies indicators were standardized: cecal intubation rate, adenoma detection rate, and withdrawal time (> 8 minutes). Asymptomatic population between 50-75 years old were enrolled and an immunological fecal occult blood test (iFOBT) was offered to them. Subjects with positive iFOBT underwent colonoscopy. All data were prospectively recorded in a database.
Results: Between June 2012 and December 2015, 16,979 individuals were enrolled, iFOBT was returned in 16,168 (compliance 95,2%). A total of 3,622 colonoscopies were performed.
In total, 320 high-risk adenomas and 146 cancer cases were diagnosed. From the latter 133 had been treated; 89 patients (67%) underwent an endoscopic resection, and 44 had surgical resection (33%). Early stage of CRC (0-I-II) was observed in 31 operated patients (70%). The adenoma detection rate was 37%.
Colonoscopy indicators: 3,225 (89%) had 7 or more points in Boston´s scale; of these 3,183 (98.6%) achieved cecal intubation, and in 3,024 (93.7%) had more than 8 minutes of withdrawal time.
Conclusions: In this CRCSP, most patients with CCR were treated by colonoscopy. Health professional´s education allows to improve iFOBT compliance, bowel preparation quality and to reach high quality colonoscopy indicators.

キーワード

臓器別:大腸・小腸

手法別:臨床試験

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