演題抄録

International Session

開催概要
開催回
第54回・2016年・横浜
 

日本の脳腫瘍診療ガイドライン

演題番号 : IS7-1

[筆頭演者]
中洲 庸子:1 

1:静岡県立静岡がんセンター・脳神経外科

 

Guidelines have become relevant for the treatment of brain tumors, due to the importance of the multidisciplinary coordination of care with medical and neuro-oncology, radiation oncology and neurosurgery. They provide a starting point where a systematic review leads to practice recommendations formulated by a panel of specialty experts.
The Japan Neurosurgical Society recommended the development of practice parameters to treat patients with brain tumor, and requested it of the Japan Society for Neuro-Oncology Guidelines Committee. Three tumors were selected initially because of their multidisciplinary nature of therapies and challenging outcomes: Glioblastoma, primary central nervous system lymphoma and brain metastasis.
These guidelines adhere to a two-tired methodology whereby levels of recommendation are directly linked to levels of evidence with detailed evidentiary tables. The committee members met regularly to assess and screen literature search results. The data from the publications were classified as for evidence level: Class I evidence was defined that provided by one or more randomized controlled clinical trials, Class II as well-designed clinical studies, Class III as cohort studies, or case controlled studies, Class IV as case reports and case series, Class V as expert opinions.
With the evidence data classified, the information was summarized as recommendation grades: Grade A was defined as a standard with strong scientific evidences, Grade B as a standard with scientific background, Grade C as practice options or advisories without scientific evidences, Grade D as a prohibited practice with scientific evidences of harm or no effect.
Brain tumor guidelines have sought to reduce unexplained variability in care while not restricting the ability of providers to deliver individualized care for patients. The guidelines provide benchmarking knowledge and show realistic evidence gaps to introduce need of future basic and clinical research.

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