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開催概要
開催回
第53回・2015年・京都
 

節外性非ホジキンリンパ腫の後方視的検討

演題番号 : WS100-4

[筆頭演者]
和泉 春香:1 
[共同演者]
長瀬 大輔:1、石原 晋:1、三井 ゆりか:1、酒井 亜紀子:1、倉石 安庸:1、加藤 元浩:1、荒井 一歩:2、名取 一彦:1

1:東邦大学医療センター大森病院血液・腫瘍科、2:東邦大学看護学部

 

[Introduction] Approximately 40% of non-Hodgkin's lymphoma (NHL) are said to be extra nodal lymphoma. Every resulting organ is characteristic about pathological findings and there is a difference in clinical outcome and prognosis. So, we investigated and report about extra nodal NHL.
[Material and Methods] The subjects were 569 patients who were diagnosed as malignant lymphoma from January 2003 to December 2014. The histopathological diagnosis was consistent with the WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues, fourth edition (2008). This study was reviewed and approved by the institutional ethics committee of Toho University Medical Center Omori Hospital.
[Results] All cases were 569 cases including male 311 cases, female 258 cases. Pathological findings, Hodgkin's lymphoma 48 cases, NHL 511 cases, Adult T cell Leukeima Lymphoma 10 cases. In NHL of 511 cases, extra nodal NHL were 212 cases, nodal NHL were 299 cases. About extranodal NHL, biopsy site largely divided 9 areas, from gastrointestinal area 66 cases, head and neck area 42 cases, respiratory area 12 cases, bone, muscle and skin area 36 cases, urological area 9 cases, abdominal organs and tumor 24 cases, central nurve system 11 cases, others 12 cases( including bonemarrow 11 cases, breast 1 case). About pathological findings, diffuse large B cell type (DLBCL) 132 cases, follicular type 9 cases, MALT 17 cases, intravascular large B cell type 11 cases, peripheral T cell lymphoma 7 cases, others 36 cases (consist of 16 pathological type). Therapy for extra nodal NHL was mainly CHOP and R-CHOP. About clinical outcome of DLBCL which accounts for the most major pathological type, as compared with nodal DLBCL, 5 year overall survival rate, extra nodal was 61.4%, nodal was 67.3%. Both group was not reached median survival time (observation period was 120 months). There was no significant diference between two groups.
[Conclusions] Extranodal NHL is heterogeneous. Case accumulation is expected.

キーワード

臓器別:造血器・リンパ

手法別:化学療法

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