演題抄録

基調講演

開催概要
開催回
第53回・2015年・京都
 

Hereditary Cancers - Update on a Growing Field

演題番号 : KL25

[筆頭演者]
Lindor Noralane M.:1 

1:Health Sciences Research, Mayo Clinic Arizona, USA

 

The introduction of next generation sequencing has shaken up the world of hereditary cancer recognition, testing and management. It has been 20 years since the discovery of the BRCA1 and BRCA2 genes yet questions still persist about risks, tumor spectrum, and optimal management options. Similarly, much has been discovered about hereditary DNA mismatch repair deficiency (Lynch syndrome, formerly called HNPCC) but a number of important questions still remain. The areas of controversy and uncertainty will be noted in this overview. A large number of newer, rarer genetic cancer predisposition syndromes have been discovered that now complicate pre-test counseling for genetic testing because available gene panels include many genes for which the tumor spectrums and risks for cancer are simply unknown. This talk seeks to increase awareness of the multiple hereditary syndromes and the importance and the challenges of incorporating genetic evaluation into an oncology practice.

前へ戻る